The indulgence of grief in the sure means of one's losing one's objects. Through it, one deviates from the three great ends of life. They, who are not contented are stupefied by the vicissitudes of fortune. The wise, are, on the other hand, unaffected by such changes. One should destroy mental grief by wisdom, as physical grief should be destroyed by medicine. Wisdom has this power. They, however, that are foolish, can never acquire equanimity of mind.